Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Medication similar to plaquenil Hydroxychloroquine and acetaminophen Hydroxychloroquine cause yellow sweat stains Hydroxychloroquine toxicity autofluorescence What is Hydroxychloroquine, and What Does It Do? According to the American College of Rheumatology, hydroxychloroquine Plaquenil, is a “disease-modifying anti-rheumatic drug DMARD,” meaning that it helps reduce the pain and swelling that come with arthritis. It can also reduce the incidence of joint damage, thus lessening the risk of. How Does Plaquenil Work For Rheumatoid Arthritis. Hydroxychloroquine Plaquenil – American College of Rheumatology – It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Plaquenil and Back pain - from FDA reports Summary Back pain is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years, also take medication Enbrel, and have Pain. This study is created by eHealthMe based on reports of 57,706 people who have side effects when taking. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Does plaquenil reduce pain Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus, How Does Plaquenil Work For Rheumatoid Arthritis Hydroxychloroquine corneaChloroquine santa cruzHydroxychloroquine light sensitivity I have been on Plaquenil for years. It has not helped me with fatigue. Things like vitamins and exercise might assist with decreasing the fatigue level. I have been on 2 Dmards and a biologic for the longest time. I also take Tramadol for pain and now Indomethicin has been added to the mix to help with stiffness. Plaquenil for fatigue and pain DailyStrength. Will you have Back pain with Plaquenil - eHealthMe. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. I started taking Plaquenil 4 weeks ago for non specific autoimmune disease as indicated by ANA. Symptoms were low grade temperature off and on for a year, joint pain and fatigue. I have already felt some relief. Some nauseau at first but less problem with fever and joint pain. But, now I have started having stomach cramps and diarrhea. I understand these may go away. Is there anything I can. It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works. How to use Plaquenil Hydroxychloroquine is usually taken with food. Plaquenil Hydroxychloroquine belongs to a group of medications known as anti-inflammatories and antimalarials. It is used alone or in combination with other anti-arthritic medications to treat rheumatoid arthritis. It helps to reduce pain, stiffness, and swelling in joints.