Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil hemangioma dermatology Multifocal erg for plaquenil Chloroquine for dogs Although the risk of bone marrow depression is low, periodic blood counts are advisable as anaemia, aplastic anaemia, agranulocytosis, a decrease in white blood cells, and thrombocytopenia have been reported. Plaquenil should be discontinued if abnormalities develop. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Introduction. Peripheral cytopenias are common in systemic lupus erythematosus SLE, but bone marrow involvement is rarely reported. Myelofibrosis is a rare disorder characterized by reticulin fibrosis of the bone marrow, which usually occurs in response to clonal proliferation of hematopoietic stem cells in myeloproliferative disorders. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil bone marrow Common and Rare Side Effects for Hydroxychloroquine Oral, Plaquenil Side Effects Common, Severe, Long Term - 200 mg of plaquenil how long to work I thought that they can cause bone marrow supression as well. Milena AskDocWeb Thanks Milena, you have added to the list. Like many other chemotherapy drugs the use of Methotrexate can cause suppression of bone marrow. Although Hydroxychloroquine Watson Laboratories may have an effect on bone marrow that side effect is rare, less than one. Drugs that Cause Bone Marrow Depression -. Bone marrow fibrosis as a feature of systemic lupus.. Hydroxychloroquine - American Osteopathic College of.. She discontinued the methotrexate and her WBC came up, so they did not feel it necessary to to a bone marrow biopsy. She started on Plaquenil. A few months ago her WBC came back dangerously low, a little over 1. She discontinued plaquenil and her WBC came up to 1.9. Her doctor recommended a bone marrow biopsy just in case. Biopsy results are back. PLAQUENIL tablets are white, to off-white, film coated tablets imprinted “PLAQUENIL” on one face in black ink. Each tablet contains 200 mg hydroxychloroquine sulfate equivalent to 155 mg base. Bone marrow failure, anemia, aplastic anemia, agranulocytosis, leukopenia, and thrombocytopenia. What Is Plaquenil? Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. What Are Side Effects of Plaquenil?