According to legend it was first brought to Europe by a Countess who had been treated with it in Peru in the 1600s. In 1820, two French chemists isolated quinine from the cinchona bark and quinine became a treatment of reference for intermittent fever throughout the world. Quinine remains an important and effective treatment for malaria today, despite sporadic observations of quinine resistance. Plaquenil consumer medicine information Oct hydroxychloroquine retinopathy How long to try plaquenil How does chloroquine work on malaria Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication. Although chloroquine-resistant P. falciparum was first reported near the India–Myanmar border in 1973, 4 chloroquine-resistant P. vivax was unknown in India until 1995, when two cases of infection with resistant P. vivax were detected in Mumbai. 5 In 1978, the National Malaria Eradication Programme now the National Vector Borne Disease. Chloroquine was being used in many areas during the study period. Earlier also, chloroquine resistance was shown by therapeutic efficacy studies, and India switched over to ACT for falciparum malaria all over the country 21. To conclude, the study showed high levels of resistance to chloroquine; and also to monodesethylamodiaquine. These compounds belonged to a new class of antimalarials, the four-amino quinolines. Research by German scientists to discover a substitute for quinine led to the synthesis in 1934 of Resochin (chloroquine) and Sontochin (3-methyl-chloroquine). Chloroquine resistance india Antimalarial drug resistance of Plasmodium falciparum in India changes., WHO Monitoring antimalarial drug resistance in India via sentinel. Chloroquine resistant malaria may be treated with Red Pages Malaria Information and Prophylaxis, by Country. Links with this icon indicate that you are leaving the CDC website. The Centers for Disease Control and Prevention CDC cannot attest to the accuracy of a non-federal website. CDC - Malaria - Travelers - Malaria Information and Prophylaxis, by Country. In vitro assessment of drug resistance in Plasmodium falciparum in five.. Chloroquine-Resistant Malaria The Journal of Infectious Diseases.. Two important currently used antimalarial drugs are derived from plants whose medicinal values had been noted for centuries artemisinin from the Qinghao plant Artemisia annua L, China, 4th century and quinine from the cinchona tree South America, 17th century.2 In India, 12‐15 million new cases of Plasmodium vivax occur each year. These cases are successfully treated with 600 mg chloroquine adult dose. We report the results of malaria treatment of a 13‐year‐old. Chloroquine resistance occurs mostly in P.falciparum Pf, but P. vivax Pv responds to Chloroquine. The following policy has been adopted in India - 1 Uncomplicated P. vivax malaria.