But Chloroquine has significantly higher rate of retinal toxicity, so it isn't used much anymore. Also, Plaquenil appears to effectively reduce flares in patients with lupus not necessarily by suppressing immunity. Read more Anxiety over potential eye problems with Hydroxychloroquine is completely unwarranted if the dose is kept below 6mg/kg (2.2lbs) of body weight. Read more See 1 more doctor answer It can cause eye problems so you need to see an ophthalmologist and peridoic screenings. Read more Results are very good, particulary when used alone and better with methotrexate. Who makes hydroxychloroquine C1q nephropathy plaquenil Plaquenil changes the way your immune system works. In some kinds of lupus, your immune system attacks your body instead of protecting it. Plaquenil tries to quiet or slow down the immune system. Before using Plaquenil, tell your doctor if you are allergic to any drugs, or if you have psoriasis, porphyria, liver disease, alcoholism, or glucose-6-phosphate dehydrogenase G-6-PD deficiency. Take Plaquenil for the full prescribed length of time for malaria. Your symptoms may improve before the infection is completely cleared. Plenty of people who are allergic to those sulfa drugs take Plaquenil without any problem. This sounds all very odd to me! Quinine? I never heard of anybody taking Quinine for lupus. One option to Plaquenil is Chloroquine and another is called Mepacrine in the UK & Quinacrine in the USA which is an alternative to the first two. Chloroquine can be substituted for Plaquenil but only in limited circumstances. Please provide more detailed information if you want a more specific answer. Read more See 1 more doctor answer Depends on what you are being treated for.... Read more While plaquenyl is a slow acting but effective drug, Prednisone is used in much higher doses in active sle. Arthritis (non-deforming) or arthralgias associated with the disease will have substantial pain relief with a dose this low. It's infusion intervals are longer, because the turnover of recptors is slower than the production of tnf-a itself. So other meds like Imuran and Cell Cept (mycophenolate mofetil) also reduce flares, but also increases infection. Read more It depends why you are taking Plaquenil in the first place. Apart from some stomach quiziies, I have never stopped this drug, as long as it demonstrated it is working. Other than that we see a few people who have increased skin pigmentation called "plaquenil ochronosis". The dirrence with Remicade (infliximab) is that it blocks the tnf-a receptor, rather than binding tnf-a itself, but it accomplishes the same thing. I have lupus am allergic to plaquenil substitute Discontinued Plaquenil.other options?, Plaquenil Uses, Dosage & Side Effects - Chloroquine phosphate malaria side effectsDoes plaquenil cause bleedingHydroxychloroquine sulfate 200 mgHydroxychloroquine cause bladder infectionsPlaquenil prsivribed by rheumatilogshrs cut in half For all of you out there. It is possible to develop an allergy to a drug you have been on for a long time. It is more common than you think. To have an allergy you must have been exposed to the allergen or an allergen that is chemically very close to it. For example Plaquenil Your body then makes a chemical that causes the allergic reaction. Allergic reaction to plaquenil DailyStrength. Plaquenil when allergic to sulfa? Lupus Forums at The Lupus Site. Plaquenil Compared to Alternatives -. C-Quinicrin is an alternative to Plaquenil that worked REALLY well for me. The last I heard it was no longer in the US, so I have been been without it and feel miserable. Has anyone found a way to buy it in Canada or elsewhere. I am hurting here in California. I cannot take Plaquenil. Mar 05, 2010 neoral, plaquenil, systemic lupus erythematosus. Responses 1 The link below has names of medicines which may be used in patients with systemic lupus erythematosus. I just wanted to let you know that I am highly allergic to sulfa drugs and have been on plaquenil for almost 8 years with no problems at all. I did accidentally take a sulfa drug about 5 years ago and still had the horrible reaction so know I'm still allergic even while being on plaquenil.