It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Does plaquenil help infertility Chloroquine ineffective on exoerythrocytic Hydroxychloroquine rheumatoid arthritis mechanism Oct 24, 2013 After just 4 days on Plaquenil, I had severe stomach cramps, no appetite, GERD pain, diarrhea and a migraine. Not sure that the migraine was related but it happened on day 4. After contacting my Rheumatologist, I was told to stop taking the drug. When I asked what other drug I could try, he said nothing -no medicine. Hello all, I am currently new to this site and ran across the discussion about stopping Plaquenil. I have been taking Plaquenil for about 8-9 months and thought that it was not helping me because I still have a fair amount of joint pain, fatigue, muscle pain and so many other issues. How to use Plaquenil. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage is also based on weight. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. Stomach pain from plaquenil Plaquenil hydroxychloroquine Basics, Side Effects & Reviews., Stopping plaquenil. DailyStrength Can hydroxychloroquine be used for mrsaPlaquenil et depressionPlaquenil blood thinnerDoes hydroxychloroquine upset your stomach Answer. You might try starting at 1/2 a tablet and work your way up slowly. Also, generic plaquenil hydroxychloroquine is often associated with more GI side effets than the name brand. Stomach problems with Plaquenil • Johns Hopkins Arthritis.. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Plaquenil Oral Uses, Side Effects, Interactions.. Side Effects Stomach cramping, diarrhea, mild to severe headaches, dizziness, bloating, gas, loss of appetite and nausea. “Side Effects Diarrhea,gas,nausea and bloating. Big mistake.off Plaquenil and have been experiencing horrible symptoms of fatigue and pain. “Side Effects Rash on neck began on day 8. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including rash, itching/swelling especially of the face/tongue/throat, dizziness, trouble breathing. This is not a complete list of possible side effects. Apr 10, 2019 Common Plaquenil side effects may include headache, dizziness, ringing in your ears; nausea, vomiting, stomach pain; loss of appetite, weight loss; mood changes, feeling nervous or irritable; skin rash or itching; or. hair loss.