They are most common among people with weak immune systems. People with certain health conditions may need to take medications with side effects that can weaken your immune system and put you at risk for fungal infections. Chloroquine phosphate nano reef Side effects stopping plaquenil The usual adult dose for treating malaria is 800 mg initially, followed by 400 mg 6-8 hours later and then 400 mg at 24 hours and 48 hours. The dose for malaria prevention is 400 mg every week starting 1 or 2 weeks before exposure and for 4 weeks after leaving the high risk area. The recommended adult dose for rheumatoid arthritis is 400-600 mg daily for 4-12 weeks followed by 200-400 mg daily. Thomas is enthusiastic about the updated guidelines, although he worries that the new dosing recommendations have not been widely disseminated to rheumatologists. “I think people with lupus can make a difference by pointing out the new guidelines to their rheumatologists,” he says. “Plaquenil is not deposited into fat,” he explains. Does Plaquenil make you tired? amethystchic 11/03/2009. Hey all. I hope everyone is having a great day. I have a question to ask anyone on plaquenil. After taking it, does it make you feel all of sudden really tired? I recently started taking it in September and it seems like after about 5-10 minutes of taking it, I feel super tired and sleepy. Fungal infections can range from mild to life-threatening. Specifically, corticosteroids and TNF (tumor necrosis factor) inhibitors are two types of medications that can increase your chances of getting a fungal infection. Does plaquenil make you immunosuppressed Does Plaquenil actually work for you? autoimmunity, Protecting your eyesight when taking Plaquenil Lupus. Hydroxychloroquine sulfate allergy Plaquenil and other anti-malarials are the key to controlling lupus long term, and some lupus patients may be on Plaquenil for the rest of their lives. For this reason, you can think of anti-malarials as a sort of “lupus life insurance.” Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. Does Plaquenil make you tired? DailyStrength. Medications that Weaken Your Immune System and Fungal.. In my opinion, Plaquenil is best considered an immunosuppressant. It’s true that it’s different than other immunosuppressants like methotrexate or cyclosporine. It does not seem to predispose to cancer development but does predispose to some infections. What is hydroxychloroquine Plaquenil, and how does it work mechanism of action? Hydroxychloroquine is classified as an anti-malarial drug. It is similar to chloroquine Aralen and is useful in treating several forms of malaria as well as lupus erythematosus and rheumatoid arthritis. On plaquenil always made me feel very bad. hate it. before my diagnosis I was tired,aneamic,stiff etc since the plaquenil I jus flare all the time. it was so bad I just came off it for several months. got so ill they wanted me to go on chemo based drugs but I did not want that either. so reluctantly went back on the plaquenil. imo its made me worse.