In particular, chloroquine and hydroxychloroquine (Plaquenil) are two such medications, with the potential for retinal toxicity. Given that the retinal damage from these medications is largely irreversible, screening by a retinal specialist is critical to detect early retinal toxicity to try and limit the extent of visual loss. Chloroquine phosphate tablets ip 500mg Hydroxychloroquine dosage lupus Indications of chloroquine Chloroquine phosphate tablets 250 mg dosage Summary Eye pain is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 10+ years, also take medication Enbrel, and have Pain. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA. Plaquenil related eye complications are not common. Plaquenil can produce pigment changes in the macula of the retina. The retina is the part of the back of the eye that you see with. The macula is the central part of the retina responsible for central fine vision. With Plaquenil related toxicity, the pigment in the macula can change and alter vision by producing blurring and distortion of objects. The American Academy of Ophthalmology has published several dosing and screening recommendations for hydroxychloroquine to avoid potential retinal toxicity, yet some patients still experience permanent vision loss resulting from hydroxychloroquine retinopathy due to improper dosing of the drug and improper screening. A study by Wolfe and Marmor of 4000 patients with rheumatoid arthritis and systemic lupus erythematosus treated with hydroxychloroquine found a prevalence of 6.8/1000 patients. Recent studies suggest a higher prevalence of hydroxychloroquine retinal toxicity than previously recognized. Layers of retina affected with plaquenil Protecting your eyesight when taking Plaquenil Lupus., Conditions Plaquenil-related Eye Problems Eugene Eye Care Malarone doxycycline chloroquine ou mefloquine People with lupus can get retinal vasculitis, which limits the blood supply to the retina, which can have significant effects on vision. The eye then attempts to repair itself, but when the retina tries to repair itself it forms new blood vessels which can form in areas of the eye that can impair vision. What Eye Problems and Conditions Are Associated With Lupus?. Despite Plaquenil dosing recommendations, retinal toxicity.. Hydroxychloroquine retinopathy A review of imaging. It’s rare for side effects to occur with Plaquenil if the medication is dosed properly Side effects Blurred vision, bull’s eye maculopathy, scotoma, vortex keratopathy, headache, accommodative dysfunction, whitening of eyelashes, phototoxicity3 One of the most significant side effects of the drug is its possibility of causing eye problems resulting in blurred or decreased vision. The most common issue is damage to the retina. It can impair your color vision or damage the retinal cells particularly in the area right around the central vision. Like all medicines, it can cause side effects. Hydroxychloroquine retinopathy. It is known that some people who take. hydroxychloroquine for more than five years and/or in high doses are at increased risk of. damage to their retina, the light sensitive layer of cells at the back of the eye. This is known as. retinal toxicity or retinopathy.