I do have anxiety disorder but have not had a panic attack in two years and certainly not waves of panic. I have since lost my appetite and can only eat a little. Taking cellcept and plaquenil What is hydroxy chloroquine What does chloroquine do in gel Plaquenil not sleeping Feb 14, 2011 Plaquenil is a first-line drug treatment meaning its the go- to med they use -the one they initially start nearly everyone on when u test positive for auto-immune & it doesn't work for everyone! I tried it for a yr w not one bit of relief. The anxiety is not a common side effect nor is the depression. I can only speak for myself and my personal experience. Plaquenil has helped me on many levels on many days. I think, for me, anyway, the depression and anxiety I often feel is due to the autoimmune issues/sjogrens. I have not noticed an increase in depression/anxiety since being on the plaquenil but that is just me. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. anxiety, depression, rare thoughts. This didn't make me happy because I really feel that looking for more medication from someone else for sudden symptoms is not a wise choice. It helped me sleep but makes me way too tired during the day -- so it is like I am anxious, panicky, and exhausted now. She said right away that she does not think it is the plaquenil and then suggested I see a psychiatrist. Plaquenil anxiety depression Anxiety and Plaquenil Has anyone experienced mood., Plaquenil causing mood changes and depression? Chloroquine bull's eye maculopathy guidelinesHydroxychloroquine and slurred speechWhat does plaquenil do to your eyesightChloroquine hemolytic transfusion I have had chronic, clinical depression my entire life which I am on meds for. The Plaquenil GREATLY effected by depression. I am no longer taking it. If you Google 'Plaquenil Depression' you will see that it has this effects on others. That's how I got to this post! Hopefully there is something else I can try to deal with my symptoms. Can Plaquenil cause Major Depression? - Treato. Plaquenil Oral Uses, Side Effects, Interactions.. Plaquenil, anxiety and depression,. Anxiety, depression and suicidal ideation in patients with rheumatoid arthritis in use of methotrexate, hydroxychloroquine, leflunomide and biological drugs. Pinho de Oliveira Ribeiro N1, Rafael de Mello Schier A, Ornelas AC, Pinho de Oliveira CM, Nardi AE, Silva AC. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Sep 13, 2019 Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects.