Malaria: Treatment of uncomplicated malaria caused by susceptible strains of Plasmodium vivax, Plasmodium malariae, Plasmodium ovale, and Plasmodium falciparum; prophylaxis of malaria in geographic areas where chloroquine resistance is not reported. Limitations of use: Hydroxychloroquine is not effective against chloroquine- or hydroxychloroquine-resistant malaria strains of Plasmodium species; not recommended for treatment of complicated malaria, malaria prophylaxis in regions with chloroquine resistance, or treatment when the Plasmodium species has not been identified; hydroxychloroquine does not prevent relapses of P. ovale infections because it is not effective against the hypnozoite forms of these parasites. Plaquenil and tongue swell Plaquenil ankylosing spondylitis Before using Plaquenil, tell your doctor if you are allergic to any drugs, or if you have psoriasis, porphyria, liver disease, alcoholism, or glucose-6-phosphate dehydrogenase G-6-PD deficiency. Take Plaquenil for the full prescribed length of time for malaria. Your symptoms may improve before the infection is completely cleared. Safe use of the drug in the treatment of juvenile arthritis has not been established. Precautions Dermatologic reactions to PLAQUENIL may occur and, therefore, proper care should be exercised when it is administered to any patient receiving a drug with a significant tendency to produce dermatitis. Pregnancy category C. Lactation Drug is concentrated in breast milk American Academy of Pediatrics committee states that it is compatible with nursing Pregnancy Categories. A Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk. B May be acceptable. Data from case reports and retrospective and open-label studies support the use of hydroxychloroquine in the treatment of cutaneous manifestations of dermatomyositis . Rheumatoid arthritis: Treatment of acute and chronic rheumatoid arthritis in adults. Plaquenil pregnancy drug class Plaquenil Hydroxychloroquine - Side Effects, Dosage., PLAQUENIL® - Food and Drug Administration Plaquenil westport ct visual field Women exposed to hydroxychloroquine for the treatment of rheumatoid arthritis or systemic lupus erythematosus during pregnancy may be enrolled in the Organization of Teratology Information Specialists OTIS Autoimmune Diseases Study pregnancy registry 877-311-8972. Patient Education. What is this drug used for? Hydroxychloroquine Professional Patient Advice -. Plaquenil hydroxychloroquine sulfate dosing, indications.. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Drugs that prolong QT interval and other arrhythmogenic drugs Plaquenil prolongs the QT interval and should not be administered with other drugs that have the potential to induce cardiac arrhythmias. Also, there may be an increased risk of inducing ventricular arrhythmias if Plaquenil is used concomitantly with other arrhythmogenic drugs. It belongs to a class of medications known as disease-modifying antirheumatic drugs DMARDs. It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known. Safety of hydroxychloroquine in pregnant patients with connective tissue diseases a study of one hundred thirty-three cases compared with a control group. Costedoat-Chalumeau N1, Amoura Z, Duhaut P, Huong DL, Sebbough D, Wechsler B, Vauthier D, Denjoy I, Lupoglazoff JM, Piette JC.