lamblia causes hemolytic anemia) 7.d (Incorrect statement is: The principal site of gametocyte formation is the human gastrointestinal tract). Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. Chloroquine and arthritis Plaquenil and systemic lupus Stopping plaquenil beforesurgery Substitutes and alternatives to chloroquine for uses like Malaria, Extraintestinal amebiasis and Lupus Chloroquine has a high affinity for tissues of the parasite and is concentrated in its cytoplasm. As a weak base, it increases the pH of the intracellular lysosome and endosome. A more acidic medium in these organelles is needed for the parasite to affect mammalian cells. As a result, chloroquine inhibits growth and development of parasites. Other adverse reactions and side effects of Aralen. There have been rare reports of severe skin reactions such as erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, and exfoliative dermatitis. Chloroquine may precipitate a severe attack of psoriasis in patients with psoriasis and may worsen porphyria. It is recommended to check if chloroquine is still effective in the region prior to using it. Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. Question related to chloroquine Questions with answers in CHLOROQUINE Science topic, Chloroquine - an overview ScienceDirect Topics Plaquenil and flagyl togetherQuizlet systemic lupus hydroxychloroquine Oct 01, 2018 Each tablet contains 500 mg of Chloroquine phosphate USP, equivalent to 300 mg Chloroquine base. Inactive Ingredients colloidal silicon dioxide, dibasic calcium phosphate, hydroxypropylmethylcellulose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate80, pregelatinized starch. Chloroquine - FDA prescribing information, side effects and uses. Aralen chloroquine Malaria Drug Side Effects & Dosage. Chloroquine Oral Tablet Drug Information, Side Effects, Faqs. Chloroquine phosphate may cause an upset stomach. Take chloroquine phosphate with food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use chloroquine phosphate exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor. Chloroquine is used to prevent or treat malaria caused by mosquito bites in countries where malaria is common. Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver. From the article I referenced above we know that Chloroquine is a chemical cousin to the FQ’s so it is entirely plausible that Chloroquine would contribute to the cumulative toxicity. Both drugs are known to be toxic to the mitochondria 3, 4.