I'm not completely pain free, but it's a lot better than it was. I've been on plaquenil since mid June I have had a lot of stress in my life so I can't determine what is causing what. Not seeing any improvements with pain but I just went to 0 prednisone 3 weeks ago. said give it a few months and if I don't see any improvement I might as well go off of it. Wanted to let you know that I was on plaquenil for about three years and I told my RA doctor that my fatigue was worse. It just seems like the fatigue is worse than it has ever been, and it doesn't seem to matter if I go to bed early or take a nap during the day. Woke up and cleaned the kitchen an hour later(my kitchen is a galley kitchen 8 ft maybe.no time) Took a nap. Early on I did get those stomach cramps and diarrhea. All my pain is tolerable and he sees no deformities so he says he doesn't see RA activity. Just because the pain is tolerable doesn't make me like it any better. He did a plaquenil test and sure enough it was low. Hydroxychloroquine and epsom salt bath Malarone doxycycline chloroquine ou mefloquine Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine sulfate is a colorless crystalline solid, soluble in water to at least 20 percent; chemically the drug is 2-4-7-Chloro-4-quinolylaminopentylethylamino ethanol sulfate 11. PLAQUENIL hydroxychloroquine sulfate tablets contain 200 mg hydroxychloroquine sulfate, equivalent to 155 mg base, and are for oral administration. Nov 09, 2018 Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America. I wake up tired in the morning, get my kids fed and off to the schoolbus, and some days that's all I can do until it's time to go pick them up and make dinner, then I collapse after the kids are put to bed. I don't know if this is just the way RA is, or if it is a side effect of the medicine. Wasn't going to eat luch because I would have to move to do it.husband bought out. Kids came home, helped with homewrok, made dinner..picked up couch(because my blanket and pillow were there) Went to bed at 9. Drowsiness hydroxychloroquine Hydroxychloroquine - Wikipedia, Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects. Hydroxychloroquine ingredientsHow long does chloroquine stay in your systemWhat is chloroquine sulphate used for Drowsiness dry mouth increased thirst loss of appetite mood changes no pulse or blood pressure numbness or tingling in the hands, feet, or lips unconsciousness Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Hydroxychloroquine - Side Effects, Dosage, Interactions.. HYDROXYCHLOROQUINE - ORAL Plaquenil side effects, medical.. Hydroxychloroquine is an antimalarial drug used to treat or prevent malaria. It is highly effective against erythrocytic forms of Plasmodium, but not effective against exoerythrocytic forms of parasites. Hydroxychloroquine is also used to treat symptoms of acute or chronic rheumatoid arthritis and lupus erythematosus. A 16-year-old girl presented to the emergency department ED with a blood pressure of 63 mm Hg by palpation, pulse of 110 beats/min, slurred speech, and drowsiness. History revealed she had taken a handful of her hydroxychloroquine 200 mg, levothyroxine, aspirin, and ibuprofen, 30 minutes before presentation. When medicines make you tired. If the kind of medication you take is not listed here, check the label for words like “may cause drowsiness.” That can help you know what to expect while you.