Can plaquenil cause bone loss

Discussion in 'Chloroquine Drug' started by Gambik, 26-Feb-2020.

  1. bivo New Member

    Can plaquenil cause bone loss


    Bone mineral density problem #1: Glucocorticoids These wonder drugs work fast to fight inflammation from rheumatoid arthritis, lupus, fibromyalgia, Lyme disease, or a nasty rash from contact dermatitis. But they’re also the most common source of bone loss from medications, according to a 2010 joint study by the University of Colorado in Denver and the College of Pharmacy & Department of Medicine at Dalhousie University in Halifax.

    Can plaquenil discolor yiur skin Will i feel worse before i feel better on plaquenil Hydroxychloroquine and alcohol consumption

    Feb 20, 2018 Osteoporosis Can Also Cause Tooth Loss. Osteoporosis can also have an impact on another area of concern as you age – your dental health. Research indicates that there’s an association between osteoporosis and bone loss in your jaws. The bone in your jaws anchor your teeth and when they become more fragile tooth loss can occur. Plaquenil is generally well-tolerated, but side effects are possible. Common side effects linked to Plaquenil include nausea and diarrhea. Taking the medication with food eases nausea for most people taking the drug. Less common side effects include skin rashes, hair thinning, and weakness. Stars. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others.

    A Canadian study, published in a 2013 issue of the journal Osteoporosis International, found that prolonged use of glucocorticoids within the last 12 months reduced bone mineral density and increased fracture risk in the participants.“The risk of bone loss continues for as long as women stay on glucocorticoids,” Wei says. Glucocorticoids (with brand names like Prednisone, Flovent, Actonel, Decadron, Aristocort and Depo-Medro) trigger gradual bone loss, by decreasing its formation, reducing calcium absorption in the intestine and increasing urinary excretion of calcium, an important skeletal nutrient.

    Can plaquenil cause bone loss

    Manage Inflammatory Arthritis and Bone Loss, Taking Plaquenil for Rheumatoid Arthritis

  2. Is plaquenil still the go drug for lupud
  3. Find information about common, infrequent and rare side effects of Plaquenil Oral.

    • Common and Rare Side Effects for Plaquenil Oral.
    • Plaquenil Hydroxychloroquine - Side Effects, Dosage..
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    Osteoporosis causes bones to become weak and brittle — so brittle that a fall or even mild stresses such as bending over or coughing can cause a fracture. Osteoporosis-related fractures most commonly occur in the hip, wrist or spine. Bone is living tissue that is constantly being broken down and replaced. Sep 13, 2019 Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur. Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use.

     
  4. TOVAR Well-Known Member

    The resource you are looking for (or one of its dependencies) could have been removed, had its name changed, or is temporarily unavailable. Psoriatic arthritis latest treatments and their place in therapy Treatments for Rheumatoid Arthritis Hydroxychloroquine Plaquenil
     
  5. ksh New Member

    400-600 mg (310-465 mg base) PO daily for 4-12 weeks; maintenance: 200-400 mg (155-310 mg base) PO daily With prolonged therapy, obtain CBCs periodically 400 mg (310 mg base) PO once or twice daily; maintenance: 200-400 mg (155-310 mg base) PO daily With prolonged therapy, obtain CBCs periodically 100-200 mg (77.5-155 mg base) PO 2-3 times/wk Take with food or milk Nausea, vomiting Headache Dizziness Irritability Muscle weakness Aplastic anemia Leukopenia Thrombocytopenia Corneal changes or deposits (visual disturbances, blurred vision, photophobia; reversible on discontinuance) Retinal damage with long-term use Bleaching of hair Alopecia Pruritus Skin and musculoskeletal pigmentation changes Weight loss, anorexia Cardiomyopathy (rare) Hemolysis (individuals with glucose-6-phosphate dehydrogenase (G-6-PD) deficiency) Prolongs QT interval Ventricular arrhythmias and torsade de pointes Vertigo Tinnitus Nystagmus Nerve deafness Deafness Irreversible retinopathy with retinal pigmentation changes (bull’s eye appearance) Visual field defects (paracentral scotomas) Visual disturbances (visual acuity) Maculopathies (macular degeneration) Decreased dark adaptation Color vision abnormalities Corneal changes (edema and opacities) Abdominal pain Fatigue Liver function tests abnormal Hepatic failure acute Urticaria Angioedema Bronchospasm Decreased appetite Hypoglycemia Porphyria Weight decreased Sensorimotor disorder Skeletal muscle myopathy or neuromyopathy Headache Dizziness Seizure Ataxia Extrapyramidal disorders such as dystonia Dyskinesia Tremor Rash Pruritus Pigmentation disorders in skin and mucous membranes Hair color changes Alopecia Dermatitis bullous eruptions including erythema multiforme Stevens-Johnson syndrome Toxic epidermal necrolysis Drug reaction with eosinophilia and systemic symptoms (DRESS syndrome) Photosensitivity Dermatitis exfoliative Acute generalized exanthematous pustulosis (AGEP); AGEP has to be distinguished from psoriasis; hydroxychloroquine may precipitate attacks of psoriasis Pyrexia Hyperleukocytosis Hypersensitivity to 4-aminoquinoline derivatives Retinal or visual field changes due to 4-aminoquinoline compounds Long-term therapy in children Not effective against chloroquine-resistant strains of P. Individual plans may vary and formulary information changes. Hydroxychloroquine Oral Uses, Side Effects, Interactions. Hydroxychloroquine Oral Route Description and Brand. Drugs & Medications A-Z - WebMD
     
  6. X-Master New Member

    Chloroquine Dosage Guide with Precautions - Kg or more 1 g chloroquine phosphate 600 mg base orally as an initial dose, followed by 500 mg chloroquine phosphate 300 mg base orally after 6 to 8 hours, then 500 mg chloroquine phosphate 300 mg base orally once a day on the next 2 consecutive days Total dose 2.5 g chloroquine phosphate 1.5 g base in 3 days Less than 60 kg

    Chloroquine MedlinePlus Drug Information