I took the drug as a treatment for sarcoidosis and one of the side effects is a reduction in white blood cells, which is what has happened to me. Plaquenil is used in the treatment of sarcoidosis but its main use is in the treatment of malaria. Generic drug for plaquenil Can swollen ankles be caused by hydroxychloroquine Can hydroxychloroquine cause weight loss Color vision changes associated with plaquenil toxicity Thanks for the replies I'm on 200mg of paquenil twice a day I think the main reason the consultant suggested stopping it for a month was because I probably came over quite wishy washy as to whether it was helping me or not and he basically said quite often the best way to tell how much it is helping is to stop it for a month and see if you feel worse which I the time I thought made sense? Plaquenil is generally well-tolerated, but side effects are possible. Common side effects linked to Plaquenil include nausea and diarrhea. Taking the medication with food eases nausea for most people taking the drug. Less common side effects include skin rashes, hair thinning, and weakness. RARE side effects. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. For the four years that I took the drug, my eye sight never bothered me and bi-annual eye tests revealed no changes. One of the side effects of taking the drug is that it affects eye sight, and eye tests, especially tests need to be done every six months. Side effects discontinuing plaquenil Plaquenil Side Effects - GoodRx, Taking Plaquenil for Rheumatoid Arthritis Plaquenil classificationChloroquine phosphate ukAre mefloquine and plaquenil the sameRheumatoid drug plaquenilPlaquenil and muscle relaxers interactions Feb 19, 2020 Common side effects may include headache, dizziness, ringing in your ears; nausea, vomiting, stomach pain; loss of appetite, weight loss; mood changes, feeling nervous or irritable; skin rash or itching; or. hair loss. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Common and Rare Side Effects for Plaquenil Oral. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. That said, my doctor had originally prescribed for me to take 100mg/day for one week and then increase to 200mg/day. When I increased to 200mg/day, I had strange side effects that caused me to go back to 100/day. Strange leg cramping, restless leg, nausea and anxiety. In a nutshell, at 200mg/day the side effects outweighed the benefits. If you arent already, split your doses up and take it with food. It may help your stomach issues. Im glad you are not stopping the plaq. Also, after a few weeks of being on it again your stomach issues may go away. This is a common side effect but usually subsides once your body adjusts to the medication. xoxox Feb 19, 2020 PLAQUENIL does not prevent relapses of P. vivax or P. ovale because it is not active against the hypnozoite forms of these parasites. For radical cure of P. vivax and P. ovale infections, concomitant therapy with an 8-aminoquinoline compound is necessary see CLINICAL PHARMACOLOGY - Microbiology.