It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Alopecia plaquenil Hydroxychloroquine and antacids Does hydroxychloroquine decrease human anti-chimeric antibody Nov 09, 2018 Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. In 1956, the U. S. Food and Drug Administration approved HCQ for symptoms of lupus and rheumatoid arthritis, particularly skin inflammation, hair loss, mouth sores, fatigue, and joint pain. Dosing. Hydroxychloroquine is generally prescribed at a daily dose of 6.5 milligrams or less per kilogram of body weight. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil and sleepiness Is lethargy and tiredness a side effect of hydroxychloroquine?, Plaquenil Side Effects Common, Severe, Long Term - Alternativesto taking plaquenilHow quickly does damage from plaquenilHydroxychloroquine 200 mg dosageIs plaquenil good or bad for kidneys Hi Phoebe, I have been on plaquenil for many years and have not experienced a sudden onset of fatigue after taking it. While those of us with lupus never truly find anything to relieve fatigue, plaquenil is suppose to help with fatigue rather than create more from what I understand. Does Plaquenil make you tired? DailyStrength. Drug spotlight on hydroxychloroquine Lupus Foundation of.. Plaquenil Oral Interactions with Other Medication. Although the words “fatigue” and “sleepiness” are often used interchangeably, they are distinct phenomena. Sleepiness refers to a tendency to fall asleep, whereas fatigue refers to an overwhelming sense of tiredness, lack of energy, and a feeling of exhaustion associated with impaired physical and/or cognitive functioning.1 Sleepiness and fatigue often coexist as a consequence of sleep. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. I have been on Plaquenil for years. It has not helped me with fatigue. Things like vitamins and exercise might assist with decreasing the fatigue level. I have been on 2 Dmards and a biologic for the longest time. I also take Tramadol for pain and now Indomethicin has been added to the mix to help with stiffness.