An audit of 100 patients seen at any of nine Canadian rheumatology clinics during early 2016 showed that 30% of patients were not on appropriate weight-based hydroxychloroquine dosages, and 13% of patients on the drug had not received a baseline retinal assessment during their first year of treatment, “We are significantly below the standard of care for appropriately dosing and screening” patients treated with hydroxychloroquine (Plaquenil), concluded Dr. Koppikar, an internal medicine physician at Queens University in Kingston, Ont. Hydroxychloroquine and yellow sweat stains Plaquenil for erosive osteoarthritis Plaquenil and chronic fatigue syndrome Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Rheumatoid Arthritis. The action of hydroxychloroquine is cumulative and may require weeks to months to achieve the maximum therapeutic effect see CLINICAL PHARMACOLOGY. Initial adult dosage 400 mg to 600 mg 310 to 465 mg base daily, administered as a single daily dose or in two divided doses. Hydroxychloroquine dosing information. Usual Adult Dose for Malaria Treatment of the acute attack 800 mg 620 mg base followed in 6 to 8 hours by 400 mg 310 mg base, then 400 mg 310 mg base once a day for 2 consecutive days; alternatively, a single dose of 800 mg 620 mg base has also been effective Although his study did not examine reasons for the compliance shortfall, Dr. HCQ comes only as 200-mg tablets, and prescribing intermediate dosages can be a challenge (although veteran clinicians know that a safe and easy way to dial down a dosage is to have the patient periodically skip a dose). In a second recently reported study, researchers from the Chicago area documented that roughly half of the 554 rheumatology patients on hydroxychloroquine (HCQ) in a regional health system and seen by an ophthalmologist during 2009-2016 received an excessive dosage of the drug (). Hydroxychloroquine renal dosing Hydroxychloroquine - Side Effects, Dosage, Interactions - Drugs., Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects. Chloroquine resistant malaria areas Hydroxychloroquine sulfate tablets can impair accommodation and cause blurring of vision. If the condition is not self-limiting, dosage may need to be temporarily reduced. Plaquenil Hydroxychloroquine Sulfate - Sanofi. Hydroxychloroquine Uses, Dosage & Side Effects -. Hydroxychloroquine Plaquenil Dosing Calculator - MDCalc. Hydroxychloroquine HCQ, a well-known anti-malarial drug, is commonly used in clinical practice for its anti-inflammatory actions. However, little is known about its role in renal ischemia. PLAQUENIL prescription and dosage sizes information for physicians and healthcare professionals. Pharmacology, adverse reactions, warnings and side effects. The ACR 2016 statement goes on to note that other authors have recommended a dosage of 6.5 mg/kg of actual body weight but capped at 400 mg/day and adjusted for renal insufficiency, and the ACR statement stops short of specifying which dosage strategy it recommends. “The AAO recommendations.