Since I have not taken it my chest feels so much better which is odd because chest pain is not listed as a side effect. Also I noticed that the Plaquenil I think was making me feel different but not in a good way. Plaquenil and liver damage Does plaquenil reduce rheumatoid arthritis Plaquenil side effects gum sores Is chloroquine in liquid I think tapering off over a month or so would be fine, but I would NOT go cold turkey on this one. Maybe your doc will want to switch you to another SNRI like Effexor to help during the taper off. And of course you can’t really cut the tabs in half due to the time-release coating. So that's the update. The lesson here is - for those who need to go off plaquenil, be careful about just going off it cold turkey. Obviously some of CAN do that, but if you don't know if you're one of them - better to be on the safe side and wean slowly. Take it from me! I am feeling much better after bumping my dose back up over the last few. I'm glad to read you're doing well on the Plaquenil but I have to ask why you're doing a taper down. If your doctor is telling you to do this, what's the reason? If you don't have to make a change, I dont think I'd mess with the dosage. I'd hate for your symptoms get worse. One of the most ill advised things I did was go off Plaquenil for a few. Did you take yourself off Plaquenil, or did your doctor tell you to go off it? Plus I will be honest the whole eye site thing even though rare has always freaked me out. I went off of it to see if I can manage not being on it as my lupus isnt as severe as other cases but already I am feeling very fatigued and my legs feel heavy if that makes sense. I can discuss alternatives with my DR at my next appt but my DR feels as though the plaq is the best bet for my level of illness. If so are you just dealing with Lupus symptoms or did you take another med? I'm on Plaquenil, and after the first week's GI upset, I have had no problems with it. How to taper off plaquenil Is it common practice to wean off plaquenil., Let me tell you what weaning down from Plaquenil is like. Can you get plaquenil in a injectionHydroxychloroquine lyme supplementsPlaquenil withdrawal headacheStarting hydroxychloroquine You really should talk to your doctor about your tapering schedule and any side effects you’re experiencing. They may want you to slow down. Plaquenil can take up 1-2 months to start working and up to six months for full effect. More information for Plaquenil can be found here. Have you been prescribed steroid treatment for your RA? Steroid treatment for RA and advice for tapering. Plaquenil taper. DailyStrength. Taking Plaquenil for Rheumatoid Arthritis. Has anyone's doctor suggested taking plaquenil to help taper off Rheum thinks that plaquenil will help me get to a lower dose of prednisone since I can't get past 7.5 mg without a flare. How do you wean yourself off of hydroxychloroquine? Asked by PawPaw1234 Updated 29 October 2012 Topics hydroxychloroquine, nabumetone, period. I'm currently wanting to stop taking this product aong with the nabumetone, I am wanting to discontinue use of both meds, should I stop abrutly or wean myself off over a period of time? Yes, if the plaquenil controls your Lupus flares, it is best to not use the prednisone. I hope you can get off of it completely, or at least take a small maintenance dose. Take it very slow, tapering off, and if you have a reaction, severe fatigue, etc, talk to your doc, about tapering down even slower.