I understand there are very significant withdrawal symptoms and I would like to stop taking Pristiq because it causes my heart to race when the time release happens. I take 50 mg per day and have done so for about 2 years. Chloroquine and malaria Plaquenil kidney pain To completely quit and go off something in one move. For example, if you were coming off drugs, you could go 'cold turkey' and just completely stop taking them rather than slowly decrease the dosage to smaller amounts over a period of time. It relies heavily on willpower. Sep 17, 2011 To completely quit and go off something in one move. For example, if you were coming off drugs, you could go 'cold turkey' and just completely stop taking them rather than slowly decrease the dosage to smaller amounts over a period of time. It relies heavily on willpower. The lesson here is - for those who need to go off plaquenil, be careful about just going off it cold turkey. Obviously some of CAN do that, but if you don't know if you're one of them - better to be on the safe side and wean slowly. Once I ran out of meds on a Thursday but was going to see my pdoc on Tuesday and thought, no biggie, I can skip a few days. My withdrawal symptoms were gross over-sensitivity to light, a really bad headache, malaise, achy all over, notably decreased mood support (I’m on a cocktail, so Pristiq is just one of 5 psycho-active meds). Managed to do this to myself again by forgetting the Pristiq in my shoulder bag (man-purse) and missing 5 days. I’ve heard that for some, you can’t go back on as it will no longer be effective once totally off. I’ve been on Pristiq for 2-1/2 years and aside from sweating, I tolerate it well. ” that of course led to the realization that I’d missed 5 doses of Pristiq. Can you go off of plaquenil cold turkey Arthritis treatment 6 reasons why I stop Methotrexate, What happens when you stop taking the drug leflunomide cold. Does plaquenil make a virus worseCan chloroquine injection terminate pregnancyCan plaquenil help with back painChloroquine side effects sleep Did you take yourself off Plaquenil, or did your doctor tell you to go off it? And as far as the vision issue goes, toxicity causing vision loss is very rare if you are on the right dose for your height and if you get regular eye exams. And those who do get toxicity have usually been on the drug for years and years. Had to stop taking Plaquenil -. Let me tell you what weaning down from Plaquenil is like.. Quitting Methotrexate Cold Turkey - Arthritis Information. May 07, 2012 my new rheumatologist recommended that I go off the plaquenil I’m on. I been on since jan 2012. I stopped taking about 5 days ago and since havn’t slept much and felt like I had the flu as well, but I was starting to get sick the same day I stopped anyways. I also have fibromyalgia so my pain is worse with lack of sleep. The Dangers of Cold Turkey Detox But imagine going through these symptoms at home, alone, or with people who have no medical training, who can’t prescribe benzodiazepines, who don’t know what to do when your withdrawal symptoms drive you to the point of pleading and begging for a drink, anything to make the pain and depression and physical and mental agony go away. I do not recommend you stop your medication cold turkey. You need to schedule an appointment with a doctor. If you have a local health clinic you could schedule an appointment with a doctor there to discuss your blood pressure and treatment plan in regards to weaning off the medication.