These changes can restrict blood flow, resulting in organ and tissue damage. There are many types of vasculitis, and most of them are rare. Would chloroquine in a sickle cell patient be harmful Puedo beber alcohol si tomo plaquenil Plaquenil drug insert Plaquenil optometry exam Answer. Plaquenil or hydroxychloroquine has been known to cause a darkened discoloration of skin and/or mucous membranes. This is considered an adverse reaction and should be discussed with your prescriber. It is important to evaluate this color change to make sure there is nothing else wrong. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. I started taking Plaquenil 4 weeks ago for non specific autoimmune disease as indicated by ANA. Symptoms were low grade temperature off and on for a year, joint pain and fatigue. I have already felt some relief. Some nauseau at first but less problem with fever and joint pain. But, now I have started having stomach cramps and diarrhea. I understand these may go away. Is there anything I can. The condition can be short term (acute) or long lasting (chronic). Vasculitis might affect just one organ, or several. Can plaquenil cause vasculitis The Risk of Retinal Toxicity with Plaquenil, Hydroxychloroquine Plaquenil How long before plaquenil works Mar 26, 2019 Uses for Plaquenil. Hydroxychloroquine is used to treat malaria. It is also used to prevent malaria infection in areas or regions where it is known that other medicines eg, chloroquine may not work. Hydroxychloroquine belongs to a group of medicines known as antimalarials. Plaquenil Advanced Patient Information -. Stomach problems with Plaquenil • Johns Hopkins Arthritis Center. Vasculitis 5 Drugs to Control This Mysterious Blood Vessel.. It turned out not to be the Plaquenil but the vasculitis hitting my optic nerves. So my doc put me on Orencia along with the methotrexate and we are keeping Plaquenil for an increase in symptoms. Of all the drugs I've taken, it's had about the least amount of side effects I've ever had. I be tit;s the vasculitis that is making you so tired. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. There's no single cause of vasculitis, and in most cases the exact cause is unknown. We know that vasculitis isn't directly inherited through the genes we get from our parents, but genetic factors do play a part as several cases can occur in the same family.