Chloroquine phosphate overdose

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  1. megachip XenForo Moderator

    Chloroquine phosphate overdose


    Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of serious side effects.

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    Chloroquine overdose is a life-threatening emergency and should be managed with cardio-respiratory and hemodynamic support, monitoring of potassium along with management of arrhythmias and convulsions, as necessary. A patient who survives the acute phase and is asymptomatic should be closely observed until all clinical features of toxicity resolve. Irreversible retinal damage observed in some patients; significant risk factors for retinal damage include daily doses of chloroquine phosphate 2.3 mg/kg of actual body weight, durations of use greater than five years, subnormal glomerular filtration, use of some concomitant drug products such as tamoxifen citrate, and concurrent macular disease. Chloroquine phosphate comes as a tablet to take by mouth. For prevention of malaria in adults, one dose is usually taken once a week on exactly the same day of the week. Your doctor will tell you how many tablets to take for each dose.

    If you already have malaria, you should still keep taking this medicine for the full time of treatment even if you begin to feel better after a few days. If you stop taking this medicine too soon, your symptoms may return. If you are taking this medicine to help keep you from getting malaria, keep taking it for the full time of treatment.

    Chloroquine phosphate overdose

    Chloroquine Phosphate chloroquine phosphate dose., Aralen, Chloroquine phosphate chloroquine dosing.

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  4. Overdose If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local.

    • Chloroquine Phosphate Bulk Uses, Side Effects..
    • Chloroquine MedlinePlus Drug Information.
    • Chloroquine - FDA prescribing information, side effects and uses.

    DOSAGE AND ADMINISTRATION. The dosage of chloroquine phosphate is often expressed in terms of equivalent chloroquine base. Each 500 mg tablet of ARALEN contains the equivalent of 300 mg chloroquine base. In infants and children the dosage is preferably calculated by body weight. Overdose. Chloroquine is very dangerous in overdose. It is rapidly absorbed from the gut. In 1961, published studies showed three children who took overdoses died within 2.5 hours of taking the drug. While the amount of the overdose was not cited, the therapeutic index for chloroquine is known to be small. Chloroquine works best when you take it on a regular schedule. For example, if you are taking it once a week to prevent malaria, it is best to take it on the same day of each week. Make sure that you do not miss any doses. If you have any questions about this, check with your doctor.

     
  5. San4es_dubna Moderator

    Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. Hydroxychloroquine Compared to Alternatives - Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects. Treating Rheumatoid Arthritis With Disease-Modifying Drugs.
     
  6. AArt Well-Known Member

    Health Issues - Drug Interactions / Side Effects Plaquenil. I was wondering if anyone has experience this while taking plaquenil. It started fri evening, pain in the upper back part of eye, with pressure and some dryness. I have a call into the dr. office and they are going to talk to the dr. and will call me back a little later this evening. thanks - Countrygal. I have been

    Plaquenil Oral Interactions with Other Medication
     
  7. hoy Moderator

    Plaquenil hydroxychloroquine sulfate dose, indications. Methotrexate Moderate Hydroxychloroquine may reduce the renal clearance of methotrexate; the exact mechanism of this interaction is unknown. The mean AUC of methotrexate was increased 52% and the mean Cmax was reduced 17% when a single dose of methotrexate was given with a dose of hydroxychloroquine 200 mg oral.

    Despite Plaquenil dosing recommendations, retinal toxicity.